Search on: KLEINE-LEVIN SYNDROME 
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Descriptor English:   Kleine-Levin Syndrome 
Descriptor Spanish:   Síndrome de Kleine-Levin 
Descriptor Portuguese:   Síndrome de Kleine-Levin 
Synonyms English:   Hypersomnia, Periodic  
Tree Number:   C10.886.425.800.200.500
F03.870.400.800.200.500
Definition English:   A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569) 
History Note English:   94 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   31370 
Unique Identifier:   D017593 

Occurrence in VHL:
 

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